Article

Prognostic Significance of DNA Polymerase Theta and Its Association with Immune Infiltration in Hepatocellular Carcinoma

2026-06-15

Abstract excerpt

<title>Abstract</title> <p>Background Hepatocellular carcinoma (HCC) is a common malignancy with a poor prognosis. DNA polymerase theta (POLQ) plays multiple roles in HCC, primarily in DNA damage repair, tumor progression, and resistance to chemoradiotherapy. However, the upstream and downstream signaling pathways regulated by POLQ, along with its association with immune cell infiltration, remain unclear. Method...

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Literature Corpus work: 66117f39-6ab9-5540-80b4-8e08130e6865
DOI: 10.21203/rs.3.rs-9607318/v1

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