Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CDT1 Is a Novel Prognostic and Predictive Biomarkers for Hepatocellular Carcinoma

24 Sept 2021

Abstract excerpt

Objective Hepatocellular carcinoma (HCC) is one of the most common malignant tumors endangering human health and life in the 21st century. Chromatin licensing and DNA replication factor 1 (CDT1) is an important regulator of DNA replication licensing, which is essential for initiation of DNA replication. CDT1 overexpression in several human cancers reportedly leads to abnormal cell replication, activates DNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to DNA Repair Mechanisms
Share to Epigenetics and DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34631549
DOI: 10.3389/fonc.2021.721644

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CDT1 Is a Novel Prognostic and Predictive Biomarkers for Hepatocellular CarcinomaPMID 34631549Read ↗

CDT1-Mediated Regulation of DNA Damage Repair and Immune-Related Target Genes Underlies Hepatocellular Carcinoma DevelopmentSemantic proximity Read ↗

MCM7 promotes cancer progression through cyclin D1-dependent signaling and serves as a prognostic marker for patients with hepatocellular carcinomaSemantic proximity Read ↗

Transcriptional Expression of Minichromosome Maintenance 10 as an Independent Negative Predictor of Survival in Hepatocellular CarcinomaSemantic proximity Read ↗

Elevated DNA Polymerase Delta 1 Expression Correlates With Tumor Progression and Immunosuppressive Tumor Microenvironment in Hepatocellular CarcinomaSemantic proximity Read ↗

Translationally Controlled Tumor Protein Induces Mitotic Defects and Chromosome Missegregation in Hepatocellular Carcinoma DevelopmentSemantic proximity Read ↗

Investigation of mitochondrial DNA methylation-related prognostic biomarkers in hepatocellular carcinoma using The Cancer Genome Atlas (TCGA) databaseSemantic proximity Read ↗

Identification of MCM4 as a Prognostic Marker of Hepatocellular CarcinomaSemantic proximity Read ↗

Effect of Upregulated DNA Replication and Sister Chromatid Cohesion 1 Expression on Proliferation and Prognosis in Hepatocellular CarcinomaSemantic proximity Read ↗

Sustained YAP1 activation induces DNA demethylation that promotes the development of hepatocellular carcinomas lacking driver gene mutationsSemantic proximity Read ↗

Advances in molecular classification and precision oncology in hepatocellular carcinoma.Semantic proximity Read ↗

Overexpression of CDT1 Is a Predictor of Poor Survival in Patients with Hepatocellular CarcinomaSemantic proximity Read ↗

Systematic Analyses of the Role of the Reader Protein of N6-Methyladenosine RNA Methylation, YTH Domain Family 2, in Liver Hepatocellular CarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.