Article

Fine needle aspiration biopsy of breast specimens effectively harvests cells for patient-derived organoids modeling breast ductal carcinoma in situ

2025-08-13

Abstract excerpt

<h4>Background</h4> Patient-derived organoids (PDOs) generated from benign breast tissue and breast carcinomas have successfully recapitulated their respective in vivo counterparts. PDOs model tumorigenesis and allow for screening of novel therapeutics personalized to individual patients. However, acquiring cells to generate PDOs is cumbersome. We demonstrate the feasibility of fine needle aspiration biopsy (FNAB...

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Literature Corpus work: f51c42db-85ce-5f66-bebe-e842f55e1a91
DOI: 10.1101/2025.08.12.669895

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