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Distinct discrepancy in breast cancer organoids recapitulation among molecular subtypes revealed by single‐cell transcriptomes analysis

1 Sept 2024

Abstract excerpt

Dear Editor, Breast cancer organoids (BCOs) are increasingly recognised as crucial tools in personalised medicine,1 yet a significant gap remains between the need for precise drug sensitivity assessments and the biological disparities observed between BCOs and primary breast cancer (PBC) tissues.2, 3 Our extensive analysis of paired single-cell RNA sequencing data has revealed a substantial preservation of...

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PMID: 39305488
DOI: 10.1002/ctm2.70023

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