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Article

Patient-Derived Xenograft-Guided Prediction of Chemotherapy Response in Triple-Negative Breast Cancer

2024-12-12

Abstract excerpt

Chemotherapy regimens for triple-negative breast cancer (TNBC) combine agents without knowing which agents drive response. Consequently, predictors derived from multi-agent regimens cannot be assumed to generalize to individual drugs or other regimens, motivating development of treatment-matched predictors. Here, we used TNBC patient-derived xenografts (PDXs) treated with carboplatin, docetaxel, or the combination...

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Literature Corpus work
dfe9d873-da8b-5d9a-863d-d620ffb4d367
DOI
10.1101/2024.12.09.627518
Open publication

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Patient-Derived Xenograft-Guided Prediction of Chemotherapy Response in Triple-Negative Breast CancerDOI 10.1101/2024.12.09.627518
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