Article

A transcriptional mechanism involving R-loop, m6A modification and RNA abasic sites regulates an enhancer RNA of <i>APOE</i>

2022-05-01

Abstract excerpt

The DNA genetic code and the RNA regulatory code determine phenotypes from gene expression to disease susceptibility. DNA sequence variants lead to phenotypic differences among individuals, while within an individual, RNA dynamically confers cell identity and responds to cellular and environmental signals. To provide regulation for different cell types and conditions, the nucleotides of RNA are modified by hundred...

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Literature Corpus work: 66053f3a-65b8-56fd-9bcb-ad247cc94a47
DOI: 10.1101/2022.05.01.489793

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