Article

Identification of genetic variants affecting vitamin D receptor binding and associations with autoimmune disease

2016-10-12

Abstract excerpt

Large numbers of statistically significant associations between sentinel SNPs and case-control status have been replicated by genome-wide association studies. Nevertheless, few underlying molecular mechanisms of complex disease are currently known. We investigated whether variation in binding of a transcription factor, the vitamin D receptor (VDR) whose activating ligand vitamin D has been proposed as a modifiable...

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Literature Corpus work: 65f0842d-517f-5ef2-970a-96b730b66397
DOI: 10.1101/080143

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