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Article

Identification of genetic variants affecting vitamin D receptor binding and associations with autoimmune disease.

Human molecular genetics - 1 Jun 2017

Gallone Giuseppe, Haerty Wilfried, Disanto Giulio, Ramagopalan Sreeram V, Ponting Chris P, Berlanga-Taylor Antonio J

Abstract excerpt

Large numbers of statistically significant associations between sentinel SNPs and case-control status have been replicated by genome-wide association studies. Nevertheless, few underlying molecular mechanisms of complex disease are currently known. We investigated whether variation in binding of a transcription factor, the vitamin D receptor (VDR), whose activating ligand vitamin D has been proposed as a...

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Identifiers

PMID: 28335003
DOI: 10.1093/hmg/ddx092
PMCID: PMC5886188

Genes

VDR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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