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The vitamin D receptor: contemporary genomic approaches reveal new basic and translational insights

26 Feb 2017

Abstract excerpt

The vitamin D receptor (VDR) is the single known regulatory mediator of hormonal 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] in higher vertebrates. It acts in the nucleus of vitamin D target cells to regulate the expression of genes whose products control diverse, cell type-specific biological functions that include mineral homeostasis. In this Review we describe progress that has been made in defining new cellular...

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PMID: 28240603
DOI: 10.1172/jci88887

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