Article

The small GTPase ARF3 controls metastasis and invasion modality by regulating N-cadherin levels

2022-04-25

Abstract excerpt

ARF GTPases are central regulators of membrane trafficking that act by controlling local membrane identity and remodelling to facilitate vesicle formation. Unravelling ARF GTPase function is complicated by the overlapping association of ARFs with guanine nucleotide exchange factors (GEFs), GTPase-activating proteins (GAPs), and numerous interactors. The extent to which redundancy is a major factor in ARF function...

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Literature Corpus work: 65ad3eca-a466-596c-93c7-e96e6ff4fbe9
DOI: 10.1101/2022.04.25.489355

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