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Article

RalA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling.

Current biology : CB - 12 Jan 2010

Balasubramanian Nagaraj, Meier Jeremy A, Scott David W, Norambuena Andrés, White Michael A, Schwartz Martin Alexander

Abstract excerpt

Anchorage dependence of cell growth is a key metastasis-suppression mechanism that is mediated by effects of integrins on growth signaling pathways. The small GTPase RalA is activated in metastatic cancers through multiple mechanisms and specifically induces anchorage independence. Loss of integr...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20005108
DOI: 10.1016/j.cub.2009.11.016
PMCID: PMC2822103

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20005108-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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