Article

ERK 1 and ERK 2 gene polymorhisms has a role in PCOS pathogenesis

2022-04-15

Abstract excerpt

<h4>Background: </h4> Ovulation is regulated by extracellular signal-regulated kinase-1 (ERK-1) and ERK-2 signaling mechanisms, and ERK-1/2 kinases modulates the function of most of the LH-regulated genes. Defective ERK kinase signaling that is secondary to a genetic problem contributes to both ovulatory dysfunction and metabolic problems in polycystic ovary syndrome (PCOS). We planned to investigate ERK-1 and ERK...

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Literature Corpus work: 65a2087a-581f-5c4c-be10-7e9f8e9e6119
DOI: 10.21203/rs.3.rs-1547878/v1

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