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Article

The importance of ERα and ERβ gene polymorphisms in PCOS.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Jul 2012

Nectaria Xita, Leandros Lazaros, Ioannis Georgiou, Agathocles Tsatsoulis

Abstract excerpt

Estrogens act through binding to estrogen receptor α (ERα) and β (ERβ). Studies in knockout mice have shown that the absence of ERα leads to the polycystic ovary syndrome (PCOS) phenotype. Furthermore, the expression of ERβ gene is lower in follicles derived from women with PCOS compared with hea...

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Identifiers

PMID: 22296324
DOI: 10.3109/09513590.2011.649811

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22296324-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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