Impact of rs2414096 polymorphism of CYP19 gene on susceptibility of polycystic ovary syndrome and hyperandrogenism in Kashmiri women.

doi:10.1038/s41598-021-92265-1

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Impact of rs2414096 polymorphism of CYP19 gene on susceptibility of polycystic ovary syndrome and hyperandrogenism in Kashmiri women.

Scientific reports - 21 Jun 2021

Ashraf Sairish, Rasool Shayaq Ul Abeer, Nabi Mudasar, Ganie Mohd Ashraf, Masoodi Shariq R, Amin Shajrul

Abstract excerpt

Polycystic ovary syndrome (PCOS) is the most common reproductive endocrine disorder in pre-menopausal women having complex pathophysiology. Several candidate genes have been shown to have association with PCOS. CYP19 gene encodes a key steroidogenic enzyme involved in conversion of androgens into estrogens. Previous studies have reported contradictory results with regard to association of SNP rs2414096 in CYP19...

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PMID: 34155264
DOI: 10.1038/s41598-021-92265-1
PMCID: PMC8217560

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