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Article

Coordination of Glucose and Glutamine Metabolism in Tendon is Lost in Aging

2024-12-20

Abstract excerpt

Tendinopathy is an age-associated degenerative disease characterized by a loss in extracellular matrix (ECM). Since glucose and glutamine metabolism is critical to amino acid synthesis and known to be altered in aging, we sought to investigate if age-related changes in metabolism are linked to changes in ECM remodeling. We exposed young and aged tendon explants to various concentrations of glucose and glutamine to...

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Identifiers and source

Literature Corpus work
658eb658-785f-5c1e-b589-cac77c788a15
DOI
10.1101/2024.12.19.629426
Open publication

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Coordination of Glucose and Glutamine Metabolism in Tendon is Lost in AgingDOI 10.1101/2024.12.19.629426
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