Transcriptome analysis of ageing in uninjured human Achilles tendon

Abstract excerpt

INTRODUCTION: The risk of tendon injury and disease increases significantly with increasing age. The aim of the study was to characterise transcriptional changes in human Achilles tendon during the ageing process in order to identify molecular signatures that might contribute to age-related degeneration. METHODS: RNA for gene expression analysis using RNA-Seq and quantitative real-time polymerase chain reaction...

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