Article

Alterations in bile acid metabolizing gut microbiota and specific bile acid genes as a precision medicine to subclassify NAFLD

2020-08-14

Abstract excerpt

<h4>Background & Aims</h4> Multiple mechanisms for the gut microbiome contributing to the pathogenesis of non-alcoholic fatty liver disease (NAFLD) have been implicated. Here, we aim to investigate the contribution and potential application for altered bile acid (BA) metabolizing microbe in NAFLD using whole metagenome sequencing (WMS) data. <h4>Methods</h4> 86 well-characterized biopsy-proven NAFLD patients and...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b0aab12d-18be-5f38-8a16-ba83704b9864
DOI: 10.1101/2020.08.14.251876

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Alterations in bile acid metabolizing gut microbiota and specific bile acid genes as a precision medicine to subclassify NAFLDDOI 10.1101/2020.08.14.251876Read

Alterations in bile acid metabolizing gut microbiota and specific bile acid genes as a precision medicine to subclassify NAFLDSemantic proximity Read

Discovery of robust and highly specific microbiome signatures of non-alcoholic fatty liver diseaseSemantic proximity Read

Gut Microbiota Patterns in Patients with Non-Alcoholic Fatty Liver Disease: A Comprehensive Assessment Using Three Analysis MethodsSemantic proximity Read

Disentangling the Progression of Non-alcoholic Fatty Liver Disease in the Human Gut MicrobiotaSemantic proximity Read

Insights from shotgun metagenomics into bacterial species and metabolic pathways associated with NAFLD in obese youthSemantic proximity Read

The role of gut microbiota in the occurrence and progression of non-alcoholic fatty liver diseaseSemantic proximity Read

Phenotyping non-alcoholic fatty liver disease by the gut microbiota: Ready for prime time?Semantic proximity Read

The role of microbiota in nonalcoholic fatty liver disease: mechanism of action and treatment strategySemantic proximity Read

Distinct gut microbiota and metabolomic profiles in HBV-related liver cirrhosis: insights into disease progressionSemantic proximity Read

Disrupted Host-Microbiota Crosstalk Promotes Nonalcoholic Fatty Liver Disease Progression by Impaired MitophagySemantic proximity Read

Gut Microbiota Profile Changes in Patients with Inflammatory Bowel Disease and Non-Alcoholic Fatty Liver Disease: A Metagenomic StudySemantic proximity Read