Article

Transcriptome- and Epigenome-Wide Association Studies of Tic Spectrum Disorder in Discordant Monozygotic Twins

2025-11-17

Abstract excerpt

Tic spectrum disorder (TSD), including Tourette syndrome and chronic tic disorder, is a childhood-onset neurodevelopmental condition with complex genetic and environmental contributions. To investigate environmentally driven mechanisms, we analyzed peripheral blood from eleven monozygotic twin pairs either discordant or concordant for TSD using RNA sequencing and DNA methylation analysis. Differential expression a...

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Literature Corpus work: 65307fd1-dbb6-53dd-b1d3-aeb0aa259766
DOI: 10.20944/preprints202511.1141.v1

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