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Hypoxia-induced LncRNA CTD-2510F5.4 facilitates hepatocellular carcinoma cell proliferation and invasion, predicts prognosis, tumor microenvironment, and drug efficacy in patients with hepatocellular carcinoma

2023-08-23

Abstract excerpt

<h4>Purpose: </h4> Hypoxia induces abnormal expression of various long non-coding RNAs (LncRNAs) highly correlated with tumorigenesis. In this study, we identified CTD-2510F5.4, a hypoxia-induced LncRNA, based on microarray and TCGA analyses, and evaluated its impact on HCC prognosis, tumor microenvironment (TME), and drug efficacy. Methods We cultured Huh7 cells in a hypoxic chamber and detected CTD-2510F5.4 exp...

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Literature Corpus work
56f5d18c-7abd-578c-bae1-cd6b929079dc
DOI
10.21203/rs.3.rs-3273010/v1
Open publication

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Hypoxia-induced LncRNA CTD-2510F5.4 facilitates hepatocellular carcinoma cell proliferation and invasion, predicts prognosis, tumor microenvironment, and drug efficacy in patients with hepatocellular carcinomaDOI 10.21203/rs.3.rs-3273010/v1
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