Article
Pre-diabetes linked microRNA miR-193b-3p targets PPARGC1A and increases lipid accumulation in hepatocytes: potential biomarker of fatty liver disease
2021-01-23
Abstract excerpt
Distinct plasma microRNA profiles associate with different disease features. Elevated plasma microRNA hsa-miR-193b-3p has been reported in patients with pre-diabetes where early liver dysmetabolism plays a crucial role. MicroRNA target databases revealed that hsa-miR-193b-3p could potentially target PPARGC1A, a master switch transcriptional co-activator that orchestrates the expression of genes involved in multipl...
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Identifiers and source
- Literature Corpus work
- 64df6a9a-531d-5c3a-8c63-20eec6d071a1
- DOI
- 10.1101/2021.01.22.427820
