Article
Steatosis and insulin resistance in hepatitis C: a way out for the virus?
World journal of gastroenterology - 28 Oct 2009
Del Campo José A, Romero-Gómez Manuel
Abstract excerpt
The hepatitis C virus (HCV) induces lipid accumulation in vitro and in vivo. The pathogenesis of steatosis is due to both viral and host factors. Viral steatosis is mostly reported in patients with genotype 3a, whereas metabolic steatosis is often associated with genotype 1 and metabolic syndrome. Several molecular mechanisms responsible for steatosis have been associated with the HCV core protein, which is able...
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