Article

Computational drug repositioning for the identification of new agents to sensitize drug-resistant breast tumors across treatments and receptor subtypes

2023-04-04

Abstract excerpt

Drug resistance is a major obstacle in cancer treatment and can involve a variety of different factors. Identifying effective therapies for drug resistant tumors is integral for improving patient outcomes. In this study, we applied a computational drug repositioning approach to identify potential agents to sensitize primary drug resistant breast cancers. We extracted drug resistance profiles from the I-SPY 2 TRIAL...

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Literature Corpus work: 64dbd0a1-f47f-5a33-9481-adbb94b9e75e
DOI: 10.1101/2023.03.30.534178

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