Article

In search of non-coding driver mutations by deep sequencing of regulatory elements in colorectal cancer

2018-01-16

Abstract excerpt

Large-scale whole cancer-genome sequencing projects have led to the identification of a handful of cis-regulatory driver mutations in cancer genomes. However, recent studies have demonstrated that very large cancer cohorts will be required in order to identify low frequency non-coding drivers. To further this endeavour, in this study, we performed highdepth sequencing across 95 colorectal cancers and matched norma...

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Literature Corpus work: 6438efee-30de-571a-8d7f-adfaf13aa0d6
DOI: 10.1101/249300

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