Back to search

Article

A complete high quality nanopore-only assembly of an XDR <i>Mycobacterium tuberculosis</i> Beijing lineage strain identifies novel variation in repetitive PE/PPE gene regions

2018-01-30

Abstract excerpt

A better understanding of the genomic changes that facilitate the emergence and spread of drug resistant M. tuberculosis strains is required. Short-read sequencing methods have limited capacity to identify long, repetitive genomic regions and gene duplications. We sequenced an extensively drug resistant (XDR) Beijing sub-lineage 2.2.1.1 “epidemic strain” from the Western Province of Papua New Guinea using long-re...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
64311459-20b4-5fb5-ba89-22c7c1eae890
DOI
10.1101/256719
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A complete high quality nanopore-only assembly of an XDR <i>Mycobacterium tuberculosis</i> Beijing lineage strain identifies novel variation in repetitive PE/PPE gene regionsDOI 10.1101/256719
A complete high-quality MinION nanopore assembly of an extensively drug-resistant Mycobacterium tuberculosis Beijing lineage strain identifies novel variation in repetitive PE/PPE gene regions.Semantic proximity
Nanopore sequencing for <i>Mycobacterium tuberculosis</i> drug susceptibility testing and outbreak investigationSemantic proximity
Multi-platform whole genome sequencing for tuberculosis clinical and surveillance applicationsSemantic proximity
Evolution and spread of a highly drug resistant strain of Mycobacterium tuberculosis in Papua New Guinea.Semantic proximity
Portable sequencing of Mycobacterium tuberculosis for clinical and epidemiological applicationsSemantic proximity
Defining the <i>Mycobacterium tuberculosis</i> Pangenome and Suggestions for a New Composite Reference SequenceSemantic proximity
Direct nanopore sequencing of <i>M. tuberculosis</i> on sputa and rescue of suboptimal results to enhance transmission surveillanceSemantic proximity
Multi-platform whole genome sequencing for tuberculosis clinical and surveillance applicationsSemantic proximity
Long-read sequencing of <i>Mycobacterial tuberculosis</i> is comparable to short-read sequencing for antimicrobial resistance prediction and epidemiological studiesSemantic proximity
Evaluation of Nanopore sequencing for Mycobacterium tuberculosis drug susceptibility testing and outbreak investigation: a genomic analysisSemantic proximity
Targeted Sequencing Workflows for Comprehensive Drug Resistance Profiling of <i>Mycobacterium tuberculosis</i> cultures using Illumina MiSeq and Nanopore MinION: Comparison of analytical and diagnostic performance, turnaround time and costSemantic proximity
Rapid and economical drug resistance profiling with Nanopore MinION for clinical specimens with low bacillary burden of Mycobacterium tuberculosisSemantic proximity
Select a neighboring publication to make it the new centre.