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Article

Evolution and spread of a highly drug resistant strain of Mycobacterium tuberculosis in Papua New Guinea.

BMC infectious diseases - 6 May 2022

Bainomugisa Arnold, Lavu Evelyn, Pandey Sushil, Majumdar Suman, Banamu Jennifer, Coulter Chris, Marais Ben, Coin Lachlan, Graham Stephen M, du Cros Philipp

Abstract excerpt

BACKGROUND: Molecular mechanisms determining the transmission and prevalence of drug resistant tuberculosis (DR-TB) in Papua New Guinea (PNG) are poorly understood. We used genomic and drug susceptibility data to explore the evolutionary history, temporal acquisition of resistance and transmission dynamics of DR-TB across PNG. METHODS: We performed whole genome sequencing on isolates from Central Public Health...

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Identifiers

PMID: 35524232
DOI: 10.1186/s12879-022-07414-2
PMCID: PMC9077924

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