Article

Bidirectional relationship between olfaction and Parkinson’s disease

2023-10-19

Abstract excerpt

<h4>Background</h4> Hyposmia (loss of smell) is a common early symptom of Parkinson’s disease (PD). The shared genetic architecture between hyposmia and PD is unknown. <h4>Methods</h4> We leveraged genome-wide association study (GWAS) results for self-assessment of ‘ability to smell’ and PD diagnosis. Linkage disequilibrium score regression (LDSC) and Local Analysis of [co]Variant Association (LAVA) were used to i...

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Literature Corpus work: 63f05c3c-c063-51f5-a96b-029926b9af1d
DOI: 10.1101/2023.10.18.23297218

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