Article
Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults.
Medicine - 1 Nov 2015
Dong Jing, Yang Jingyun, Tranah Greg, Franceschini Nora, Parimi Neeta, Alkorta-Aranburu Gorka, Xu Zongli, Alonso Alvaro, Cummings Steven R, Fornage Myriam, Huang Xuemei, Kritchevsky Stephen, Liu Yongmei, London Stephanie, Niu Liang, Wilson Robert S, De Jager Philip L, Yu Lei, Singleton Andrew B, Harris Tamara, Mosley Thomas H, Pinto Jayant M, Bennett David A, Chen Honglei
Abstract excerpt
Olfactory dysfunction is common among older adults and affects their safety, nutrition, quality of life, and mortality. More importantly, the decreased sense of smell is an early symptom of neurodegenerative diseases such as Parkinson disease (PD) and Alzheimer disease. However, the genetic determinants for the sense of smell have been poorly investigated. We here performed the first genome-wide meta-analysis on...
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