Article
Impaired sense of smell and color discrimination in monogenic and idiopathic Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society - 15 Nov 2010
Kertelge Lena, Brüggemann Norbert, Schmidt Alexander, Tadic Vera, Wisse Claudia, Dankert Sylwia, Drude Laura, van der Vegt Joyce, Siebner Hartwig, Pawlack Heike, Pramstaller Peter P, Behrens Maria Isabel, Ramirez Alfredo, Reichel Dirk, Buhmann Carsten, Hagenah Johann, Klein Christine, Lohmann Katja, Kasten Meike
Abstract excerpt
Olfaction is typically impaired in idiopathic Parkinson's disease (IPD), but its role is uncertain in monogenic PD. Diminished color discrimination has been suggested as another early sign of dopaminergic dysfunction but not been systematically studied. Furthermore, it is unknown whether both deficits are linked. We examined 100 patients with IPD, 27 manifesting mutation carriers (MC), 20 nonmanifesting mutation...
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