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Article

Human olfaction: from genomic variation to phenotypic diversity.

Trends in genetics : TIG - 1 Apr 2009

Hasin-Brumshtein Yehudit, Lancet Doron, Olender Tsviya

Abstract excerpt

The sense of smell is a complex molecular device, encompassing several hundred olfactory receptor proteins (ORs). These receptors, encoded by the largest human gene superfamily, integrate odorant signals into an accurate 'odor image' in the brain. Widespread phenotypic diversity in human olfaction is, in part, attributable to prevalent genetic variation in OR genes, owing to copy number variation, deletion...

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PMID: 19303166
DOI: 10.1016/j.tig.2009.02.002

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