Article

Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation

2023-06-30

Abstract excerpt

<h4>ABSTRACT</h4> Partial reprogramming by cyclic short-term expression of Yamanaka factors holds promise for shifting cells to younger states and consequently delaying the onset of many diseases of aging. However, the delivery of transgenes and potential risk of teratoma formation present challenges for in vivo applications. Recent advances include the use of cocktails of compounds to reprogram somatic cells, b...

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Literature Corpus work: 63d04214-2db3-5a9a-9b20-7c14f375fc7d
DOI: 10.1101/2023.06.30.546730

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