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HucMSC-EVs Facilitate In Vitro Development of Maternally Aged Preantral Follicles and Oocytes

2 Mar 2023

Abstract excerpt

Follicle developmental capacity and oocyte quality decline with advanced maternal age. Extracellular vesicles from human umbilical cord mesenchymal stem cells (HucMSC-EVs) act as a potential therapeutic product in the treatment of age-related ovarian dysfunction. In vitro culture (IVC) of preantral follicles is a useful method for understanding the mechanism of follicle development and is a promising means for...

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PMID: 36862330
DOI: 10.1007/s12015-022-10495-w

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