Article

Genome-wide meta-analysis of iron status biomarkers and the effect of iron on all-cause mortality in HUNT

2021-09-23

Abstract excerpt

Iron is essential for many biological processes, but iron levels must be tightly regulated to avoid harmful effects of both iron deficiency and overload. Here, we perform genome-wide association studies on four iron related biomarkers (serum iron, serum ferritin, transferrin saturation, total iron binding capacity) in the Trøndelag Health Study (HUNT), the Michigan Genomics Initiative (MGI) and the SardiNIA study,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 638d9598-beb6-53d1-836d-310b5bf8af71
DOI: 10.1101/2021.09.20.21262960

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genome-wide meta-analysis of iron status biomarkers and the effect of iron on all-cause mortality in HUNTDOI 10.1101/2021.09.20.21262960Read

Genome-wide meta-analysis of iron status biomarkers and the effect of iron on all-cause mortality in HUNT.Semantic proximity Read

Novel loci and biomedical consequences of iron homoeostasis variation.Semantic proximity Read

Genome-wide association study identifies genetic loci associated with iron deficiency.Semantic proximity Read

Associations of genetically determined iron status across the phenome: A mendelian randomization studySemantic proximity Read

Genome-Wide Meta-Analysis of 1 896 991 Individuals Identifies 31 Novel Risk Loci for Iron Deficiency Anemia.Semantic proximity Read

A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis.Semantic proximity Read

Genetic and lifestyle modifiers of haemochromatosis-related clinical outcomes in HFE C282Y homozygotes: prospective cohort study in UK BiobankSemantic proximity Read

A genome-wide association analysis of serum iron concentrations.Semantic proximity Read

Common and ethnic-specific genetic determinants of hemoglobin concentration between Taiwanese Han Chinese and European Whites: findings from comparative two-stage genome-wide association studies.Semantic proximity Read

Genetic Variants Affecting Iron Metabolism in Healthy Adults: A Systematic Review to Support Personalized Nutrition Strategies.Semantic proximity Read

The Causal Effects of Blood Iron and Copper on Lipid Metabolism Disease: Evidence from Phenome-wide Mendelian Randomization StudySemantic proximity Read

Associations between single nucleotide polymorphisms in iron-related genes and iron status in multiethnic populations.Semantic proximity Read