Wild mice: an ever-increasing contribution to a popular mammalian model.

doi:10.1016/s0168-9525(02)00007-0

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Article

Wild mice: an ever-increasing contribution to a popular mammalian model.

Trends in genetics : TIG - 1 Jan 2003

Guénet Jean Louis, Bonhomme François

Abstract excerpt

Classical laboratory inbred strains of mice have been extremely helpful for research in immunology and oncology, and more generally, for the analysis of complex traits. Unfortunately, because they all derive from a relatively small pool of ancestors, their genetic polymorphism is rather limited. However, recently strains belonging to different species of Mus have been established from wild progenitors. These are...

Topics

Animals
Behavior, Animal
Biological Evolution
Chromosomes
Epistasis, Genetic
Genetic Variation
Mice
Mice, Inbred Strains
Phylogeny
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 12493245
DOI: 10.1016/s0168-9525(02)00007-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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