Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Complete overview of protein-inactivating sequence variations in 36 sequenced mouse inbred strains.

Proceedings of the National Academy of Sciences of the United States of America - 22 Aug 2017

Timmermans Steven, Van Montagu Marc, Libert Claude

Abstract excerpt

Mouse inbred strains remain essential in science. We have analyzed the publicly available genome sequences of 36 popular inbred strains and provide lists for each strain of protein-coding genes that acquired sequence variations that cause premature STOP codons, loss of STOP codons and single nucleotide polymorphisms, and short in-frame insertions and deletions. Our data give an overview of predicted defective...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Variation
Share to Genome

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genomics

Share to High-Throughput Nucleotide Sequencing

Share to Mice, Inbred C57BL

Share to Mice, Inbred Strains

Share to Proteins

Share to Species Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 28784771
DOI: 10.1073/pnas.1706168114
PMCID: PMC5576813

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Complete overview of protein-inactivating sequence variations in 36 sequenced mouse inbred strains.PMID 28784771Read ↗

Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J.Semantic proximity Read ↗

Mousepost 2.0, a major expansion of the resource.Semantic proximity Read ↗

Whole-genome sequence of the C57L/J mouse inbred strain.Semantic proximity Read ↗

Efficient analysis of mouse genome sequences reveal many nonsense variants.Semantic proximity Read ↗

Polymorphic SNPs, short tandem repeats and structural variants are responsible for differential gene expression across C57BL/6 and C57BL/10 substrainsSemantic proximity Read ↗

A resource of targeted mutant mouse lines for 5,061 genesSemantic proximity Read ↗

Mouse protein coding diversity: What's left to discover?Semantic proximity Read ↗

Sequence-based characterization of structural variation in the mouse genome.Semantic proximity Read ↗

A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains.Semantic proximity Read ↗

Variation in the Spectrum of New Mutations among Inbred Strains of Mice.Semantic proximity Read ↗

Whole exome sequencing of wild-derived inbred strains of mice improves power to link phenotype and genotype.Semantic proximity Read ↗

Into the Wild: A novel wild-derived inbred strain resource expands the genomic and phenotypic diversity of laboratory mouse modelsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.