Article

Telomere-to-telomere assembly detects genomic diversity in Canadian strains of <i>Borrelia burgdorferi</i>

2025-07-20

Abstract excerpt

Borrelia burgdorferi, the bacteria causing Lyme disease, has a complex genome comprising a linear chromosome and a combination of linear and circular plasmids. The atypical hairpin structure at the telomere of linear replicons and the highly paralogous plasmids make the genome assembly challenging. We developed a genome assembly pipeline using Oxford Nanopore Technologies (ONT) long read and Illumina short read to...

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Literature Corpus work: eeaf1940-ff26-563c-b2c5-2e4f632bb38a
DOI: 10.1101/2025.07.18.665644

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