Article

Conditional prediction of consecutive tumor evolution using cancer progression models: What genotype comes next?

2020-12-16

Abstract excerpt

Accurate prediction of tumor progression is key for adaptive therapy and precision medicine. Cancer progression models (CPMs) can be used to infer dependencies in mutation accumulation from cross-sectional data and provide predictions of tumor progression paths. However, their performance when predicting complete evolutionary trajectories is limited by violations of assumptions and the size of available data sets....

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Literature Corpus work: 62ffbf95-6af4-5611-ae51-4443f2389cb4
DOI: 10.1101/2020.12.16.423099

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