Article

PMCE: efficient inference of expressive models of cancer evolution with high prognostic power

2014-08-22

Abstract excerpt

<h4>Motivation</h4> Driver (epi)genomic alterations underlie the positive selection of cancer subpopulations, which promotes drug resistance and relapse. Even though substantial heterogeneity is witnessed in most cancer types, mutation accumulation patterns can be regularly found and can be exploited to reconstruct predictive models of cancer evolution. Yet, available methods cannot infer logical formulas connect...

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Literature Corpus work: a053de45-007d-518c-a147-46a9b79f7f58
DOI: 10.1101/008326

Open publication

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