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Article

Conditional prediction of consecutive tumor evolution using cancer progression models: What genotype comes next?

PLoS computational biology - 1 Dec 2021

Diaz-Colunga Juan, Diaz-Uriarte Ramon

Abstract excerpt

Accurate prediction of tumor progression is key for adaptive therapy and precision medicine. Cancer progression models (CPMs) can be used to infer dependencies in mutation accumulation from cross-sectional data and provide predictions of tumor progression paths. However, their performance when predicting complete evolutionary trajectories is limited by violations of assumptions and the size of available data...

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Identifiers

PMID: 34932572
DOI: 10.1371/journal.pcbi.1009055
PMCID: PMC8730404

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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