Article

htert expression correlates withMYC over-expression in human prostate cancer

2000-03-20

Abstract excerpt

Expression of the telomerase catalytic sub-unit (htert) constitutes a key step in the development of human cancer. Although htert regulation is still unclear, several studies suggest that c-myc may activate its expression. Prostate cancer is one of the most common malignancies among men in Western countries. Since de-regulated expression of myc as well as telomerase activation may contribute to the pathogenicity o...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 62e4cc06-0f3c-51cb-b0c2-dad753f9f13b
DOI: 10.1002/(sici)1097-0215(20000320)89:2<172::aid-ijc12>3.0.co;2-8

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

htert expression correlates withMYC over-expression in human prostate cancerDOI 10.1002/(sici)1097-0215(20000320)89:2<172::aid-ijc12>3.0.co;2-8Read

htert expression correlates with MYC over-expression in human prostate cancerSemantic proximity Read

MYC drives overexpression of telomerase RNA ( hTR / TERC ) in prostate cancerSemantic proximity Read

Immortalization of Primary Human Prostate Epithelial Cells by c-MycSemantic proximity Read

Genistein Represses Telomerase Activity via Both Transcriptional and Posttranslational Mechanisms in Human Prostate Cancer CellsSemantic proximity Read

Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesisSemantic proximity Read

Unopposed c-MYC expression in benign prostatic epithelium causes a cancer phenotype.Semantic proximity Read

Myc confers androgen-independent prostate cancer cell growthSemantic proximity Read

Myc confers androgen-independent prostate cancer cell growthSemantic proximity Read

Expression Profile of the Telomeric Complex Discriminates between Benign and Malignant PheochromocytomaSemantic proximity Read

In Vivo Regulation of hTERT Expression and Telomerase Activity by Androgen.Semantic proximity Read

Prostatic neoplasia in transgenic mice with prostate-directed overexpression of the c-myc oncoproteinSemantic proximity Read

Over-expression and amplification of the c-myc gene in human urothelial carcinomaSemantic proximity Read