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Article

htert expression correlates with MYC over-expression in human prostate cancer

20 Mar 2000

Abstract excerpt

Expression of the telomerase catalytic sub-unit (htert) constitutes a key step in the development of human cancer. Although htert regulation is still unclear, several studies suggest that c-myc may activate its expression. Prostate cancer is one of the most common malignancies among men in Western countries. Since de-regulated expression of myc as well as telomerase activation may contribute to the pathogenicity...

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PMID: 10754496
DOI: 10.1002/(sici)1097-0215(20000320)89:2<172::aid-ijc12>3.3.co;2-#

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