Article

Fusion Detection in Microsecretory Adenocarcinoma and Mucoepidermoid Carcinoma Using Chromogenic RNA In Situ Hybridization: A Promising Alternative to DNA-Based Fluorescence In-Situ Hybridization

2022-10-23

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Recent advances in molecular genetics have dramatically improved our understanding of the pathophysiology and classification of salivary gland tumors. The identification of recurrent oncogenic fusions has been especially helpful in distinguishing entities with overlapping histomorphology. <h4>Methods</h4> Chromogenic RNA in situ hybridization (RNA-ISH) using BaseScope™ technol...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 62c7d5fc-aa45-5724-b150-d63afa07e18f
DOI: 10.1101/2022.10.22.22281354

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Fusion Detection in Microsecretory Adenocarcinoma and Mucoepidermoid Carcinoma Using Chromogenic RNA In Situ Hybridization: A Promising Alternative to DNA-Based Fluorescence In-Situ HybridizationDOI 10.1101/2022.10.22.22281354Read

NanoString nCounter-based assay for detection of fusion-associated salivary gland tumorsSemantic proximity Read

<i>MECT1-MAML2</i> Fusion Transcript Defines a Favorable Subset of Mucoepidermoid CarcinomaSemantic proximity Read

Targeted RNA sequencing in the routine clinical detection of fusion genes in salivary gland tumorsSemantic proximity Read

Role ofCRTC1/MAML2Translocation in the Prognosis and Clinical Outcomes of Mucoepidermoid CarcinomaSemantic proximity Read

RNA sequencing of esophageal adenocarcinomas identifies novel fusion transcripts, including NPC1‐MELK, arising from a complex chromosomal rearrangementSemantic proximity Read

Salivary mucoepidermoid carcinoma: histological variants, grading systems, CRTC1/3‐MAML2 fusions, and clinicopathological featuresSemantic proximity Read

Correlation of Crtc1/3-Maml2 fusion status, grade and survival in mucoepidermoid carcinoma.Semantic proximity Read

Comparative Analysis of Molecular Testing Methods for FGFR2 Fusion/Rearrangement in Intrahepatic CholangiocarcinomaSemantic proximity Read

HER2 and EGFR gene copy number alterations are predominant in high-grade salivary mucoepidermoid carcinoma irrespective of MAML2 fusion status.Semantic proximity Read

Detection of salivary gland and sinonasal fusions by a next‐generation sequencing based, ligation‐dependent, multiplex RT‐PCR assaySemantic proximity Read

Fluorescence in situ hybridization for detection of MAML2 rearrangements in oncocytic mucoepidermoid carcinomas: utility as a diagnostic testSemantic proximity Read

Primary intraosseous mucoepidermoid carcinoma of the jaw: Reappraisal of The MD Anderson Cancer Center experienceSemantic proximity Read