Detection of salivary gland and sinonasal fusions by a next‐generation sequencing based, ligation‐dependent, multiplex RT‐PCR assay

Abstract excerpt

AIMS: The discovery of tumour type-specific gene fusion oncogenes in benign and malignant salivary gland and sinonasal (SGSN) tumours has significantly increased our knowledge about their molecular pathology and classification. METHODS AND RESULTS: We developed a new targeted multiplexed next-generation sequencing (NGS)-based method that utilizes ligation dependent reverse-transcriptase polymerase chain reaction...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Head and Neck Surgical Oncology
• Share to Salivary Gland Disorders and Functions
• Share to Salivary Gland Tumors Diagnosis and Treatment