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Crispr-cas 12a combination to alleviate the false-positive in loop-mediated isothermal amplification-based diagnosis of Neisseria meningitidis

2020-11-17

Abstract excerpt

Loop mediated Isothermal amplicafication (LAMP) was recently suggested as a diagnostic tool for the identification of Neisseria meningitides . Howevere, this isothermal amplification is challenged by the fact its amplification leads to risks of obtaining false-positive results. Whereas, with abilities to accurately recognize specific sequence, the CRISPR/Cas12a can forms complexes with cognate RNA sensors and clea...

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Literature Corpus work
62999e2b-4a97-54a4-90aa-aad55d1a2bdb
DOI
10.21203/rs.3.rs-108208/v1
Open publication

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