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Article

Development of a CRISPR/Cas-Based Detection Platform for Tracking Decreased Susceptibility to Cephalosporins in Neisseria gonorrheae.

Analytical chemistry - 16 Sept 2025

Zhao Ziyuan, Li Yamei, Xiu Leshan, Wang Feng, Peng Junping

Abstract excerpt

Gonorrhea has become an escalating public health issue due to the rapid emergence of antimicrobial resistance (AMR). Developing efficient and accurate detection of resistant strains is urgently needed for their management and treatment. We have developed the Multiplex Integrated RPA-CRISPR/Cas12a detection Assay (MIRCA) for simultaneous detection of Neisseria gonorrheae (Ng) and mutations with decreased...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40748632
DOI: 10.1021/acs.analchem.5c01400

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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