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HNB-RT-LAMP Coupled with CRISPR/Cas12a for the Simultaneous Detection of Enteroviruses and Enterovirus A71 in a Single Tube

26 Mar 2025

Abstract excerpt

High Resolution Image Download MS PowerPoint Slide Background: Enterovirus (EV) infections encompass a spectrum of diseases, with severe cases often linked to enterovirus A71 (EV-A71), highlighting its significance in EV screening. Although the CRISPR/Cas12a diagnostic system shows promise in nucleic acid detection, enhancing specificity and sensitivity when combined with reverse transcription-loop-mediated...

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PMID: 40224480
DOI: 10.1021/acsomega.4c09729

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