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CRISPR/Cas-based nucleic acid detection strategies: Trends and challenges

1 Feb 2024

Abstract excerpt

CRISPR/Cas systems have become integral parts of nucleic acid detection apparatus and biosensors. Various CRISPR/Cas systems such as CRISPR/Cas9, CRISPR/Cas12, CRISPR/Cas13, CRISPR/Cas14 and CRISPR/Cas3 utilize different mechanisms to detect or differentiate biological activities and nucleotide sequences. Usually, CRISPR/Cas-based nucleic acid detection systems are combined with polymerase chain reaction,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38390187
DOI: 10.1016/j.heliyon.2024.e26179

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