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Metformin inhibits cervical cancer cell proliferation by modulating PI3K/Akt-induced major histocompatibility complex class I-related chain A gene expression

2020-06-22

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold>Recent studies have shown that the classic hypoglycemic drug metformin inhibits tumor growth; however, the underlying mechanism remains unclear. We previously showed that metformin disrupts the sponge effect of long non-coding RNA MALAT1/miR-142-3p to inhibit cervical cancer cell proliferation. In this study, we interrogated the ability of metformin to modulate t...

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Literature Corpus work
448e9f3c-b957-5218-a66b-4f1a81ed4323
DOI
10.21203/rs.3.rs-31160/v3
Open publication

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Metformin inhibits cervical cancer cell proliferation by modulating PI3K/Akt-induced major histocompatibility complex class I-related chain A gene expressionDOI 10.21203/rs.3.rs-31160/v3
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