Article

A statistical approach to identify regulatory DNA variations

2023-02-03

Abstract excerpt

Non-coding variations located within regulatory elements may alter gene expression by modifying Transcription Factor (TF) binding sites and thereby lead to functional consequences like various traits or diseases. To understand these molecular mechanisms, different TF models are being used to assess the effect of DNA sequence variations, such as Single Nucleotide Polymorphisms (SNPs). However, few statistical appro...

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Literature Corpus work: 6253472b-58b9-5652-981b-852bae40e382
DOI: 10.1101/2023.01.31.526404

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