Article

A Computational Cancer GWAS Screen Identifies Structural Variants Near STAG3 at a Colorectal Cancer Risk Locus

2026-06-23

Abstract excerpt

<title>Abstract</title> <p> Structural variants, deletions, duplications, and insertions larger than 50 base pairs are absent from genotyping arrays and have been excluded from most cancer genome-wide association studies. This gap is most severe at meiosis-specific gene loci, which are repeat-rich and poorly resolved by short-read sequencing. A computational screen was performed across 31 meiosis-related genes u...

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Literature Corpus work: 621b3c6d-d7c5-5c44-8d92-507284814808
DOI: 10.21203/rs.3.rs-9890162/v1

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