Article

A GYS2/p53 negative feedback loop restricts tumor growth in HBV-related hepatocellular carcinoma

2018-07-20

Abstract excerpt

Hepatocarcinogenesis is attributed to the reprogramming of cellular metabolism as consequence of the alteration in metabolite-related gene regulation. Identifying the mechanism of aberrant metabolism is of great potential to provide novel targets for the treatment of hepatocellular carcinoma (HCC). Here, we demonstrated that glycogen synthase 2 (GYS2) restricted tumor growth in HBV-related HCC via a negative feedb...

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Literature Corpus work: 6211f0f2-098b-53f4-af15-30085b4adae2
DOI: 10.1101/373761

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